6/15/2023 0 Comments Max 120 cigarettesBecause dependence on tobacco is produced primarily through the pharmacological effects of nicotine ( Benowitz, 2009), an understanding of the pharmacology (i.e., disposition kinetics, metabolism, and pharmacodynamics) of nicotine, concentration of nicotine in commercial e-cigarette liquids and aerosols, systemic nicotine exposure among users, and factors that may affect nicotine exposure are essential to understanding the potential addictiveness of e-cigarettes. According to the 1988 Surgeon General’s report The Health Consequences of Smoking: Nicotine Addiction, “Nicotine is the drug in tobacco that causes addiction” ( HHS, 1988, p. Electronic cigarettes are designed to deliver a nicotine-containing aerosol to the user.
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